Cognitive dysfunction in major depressive disorder: effects on psychosocial functioning and implications for treatment.
نویسندگان
چکیده
M depressive disorder is a common condition with a high rate of recurrence, chronicity, and staggering economic burden, including disability in the workforce.1 In 2010, MDD was the second leading medical cause of burden globally, with highest estimates of disability in people of working age.2 In Canada, the annual prevalence of MDD is 3% to 4% overall, and 79% of people with MDD report some interference with work functioning, either decreased work productivity and (or) absenteeism.1 In addition to work impairment, the psychosocial impact of MDD often affects a person’s level of functioning in family and social relationships. While there is clearly an association between improvement in depressive symptoms and functioning, symptom improvement can also be dissociated from functional improvement and work loss.3,4 Hence there has been increasing recognition that symptomatic remission is an insufficient goal of treatment for MDD and that return to premorbid psychosocial functioning should be targeted.5
منابع مشابه
Editorial: cognitive dysfunction in major depressive disorder - pathophysiology, clinical implications and treatment opportunities).
Cognitive impairments in major depressive disorder (MDD) are consistent and replicable findings with significant clinical impact. The aggregated estimated effect size of cognitive deficits in MDD is small to medium. However, pronounced deficits in executive function is evident in ~ 20-30% of adult MDD patients. Other replicated deficits are in the domains of working memory, attention, and psych...
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ورودعنوان ژورنال:
- Canadian journal of psychiatry. Revue canadienne de psychiatrie
دوره 59 12 شماره
صفحات -
تاریخ انتشار 2014